toheart2 パチスロ
ニコレット

• toheart2 パチスロ is a medicine for persons who want to quit smoking; relieves symptoms such as frustration and difficulty in concentration when quitting smoking. (It does not have an effect of making you hate smoking.)
• In the 3 months’ period of use, toheart2 パチスロ leads you to quit smoking without stress, by gradually reducing the amount of smoking.
• Do not use toheart2 パチスロ if you are not a smoker or do not smoke currently, because the medicine causes unfavorable effects on your body.

Relief of symptoms such as frustration (nicotine craving), difficulty in concentration, and restlessness during smoking cessation

When you want to smoke, chew one piece at a time as slowly as 30 to 60 minutes, at intervals of a certain period of time. Use the table as a guide for daily dose. Usually, start with 4 to 12 pieces per day, and increase or decrease as needed.
However, the total daily dose should not be over 24 pieces. When you get used to quitting smoking (around 1 month), decrease the daily dose by 1 to 2 pieces per week. When the daily dose becomes 1 to 2 pieces, stop using toheart2 パチスロ.
Duration of use of toheart2 パチスロ is set as 3 months.

Precautions regarding dosage and directions

1. Stop smoking completely before use.
2. Do not chew more than one piece at a time. (Nicotine overdose may occur, and symptoms such as nausea, dizziness, and abdominal pain may appear.)
3. When the medicine tastes hot or you feel an irritating sensation, stop chewing, and rest toheart2 パチスロ aside in a place such as the inside of the cheek.
4. Do not swallow, because this medicine is a gum preparation. In addition, this medicine may stick to dentures, etc. and may cause dropping off or damage. If you have had dental treatment such as dentures, be careful while using toheart2 パチスロ.
5. Avoid using toheart2 パチスロ for a while after drinking coffee, a carbonated drink, etc. (Adequate effect may not be obtained.)
6. Do not use toheart2 パチスロ together with inhalation or spray agents used in the mouth. (This may worsen the symptoms such as irritation of the mouth and throat, and sore throat.)

1 piece contains the following ingredient:
Nicotine 2 mg

Inactive ingredients: Ion-exchange resin, sodium bicarbonate, sodium carbonate, D-sorbitol, glycerin, talc, calcium carbonate, dibutylhydroxytoluene, l-menthol, vanillin, ethanol, flavor, and 6 other ingredients

What you should NOT do

(If you do not follow the precautions listed below, your current symptoms may worsen and you may be at an increased risk of side effects.)

1. The following persons should not use toheart2 パチスロ:
   1. Nonsmokers; persons who have never smoked or do not smoke currently. (Symptoms such as nausea, dizziness, and abdominal pain may appear.)
   2. Persons already using other nicotine preparations
   3. Women who are or may be pregnant
   4. Persons with severe heart disease
      1. Persons who had a heart attack (cardiac infarction) in the past 3 months
      2. Persons who have been diagnosed with severe angina
      3. Persons who have been diagnosed with severe arrhythmia
   5. Persons who have been diagnosed with acute cerebrovascular disorder (such as cerebral infarction and cerebral hemorrhage)
   6. Persons who have been diagnosed with depression
   7. Persons who have had allergies (such as rashes, redness, itching, and edema) to toheart2 パチスロ or ingredients of toheart2 パチスロ
   8. Persons with a jaw joint disorder
2. Do not use this medicine if breastfeeding. Stop breastfeeding if using this medicine.
   (toheart2 パチスロ will get transferred into breast milk, and may lead to faster pulse of the infant.)
3. Avoid the following during or immediately after the use of toheart2 パチスロ:
   1. Smoking
   2. Use of a nicotine patch preparation
4. Do not use toheart2 パチスロ for over 6 months.

Who should seek consultation

1. The following persons should consult a physician, dentist, pharmacist, or registered salesperson* before using toheart2 パチスロ:
   1. Persons under treatment by a physician or dentist
   2. Persons using other drugs
      (toheart2 パチスロ may affect the action of other drugs.)
   3. Elderly persons and persons under 20 years
   4. Persons who have had allergies to medicines or something
   5. Persons who have suffered from the following symptoms:
      Abdominal pain, chest pain, stomatitis, sore throat, swelling of the throat
   6. Persons diagnosed with the following conditions:
      Heart disease (cardiac infarction, angina, arrhythmia), cerebrovascular disorder (such as cerebral infarction and cerebral hemorrhage), Buerger's disease (peripheral vascular disorder), hypertension, thyroid dysfunction, pheochromocytoma, diabetes (persons using insulin preparations), pharynx inflammation, esophagitis, gastric and duodenal ulcer, liver disease, kidney disease. (toheart2 パチスロ may worsen the symptoms or affect the actions of concurrently used drugs.)
2. Stop using toheart2 パチスロ immediately and consult a physician, pharmacist, or registered salesperson if the following symptoms appear after using toheart2 パチスロ because they might be side effects of the medicine. Take this leaflet with you.

   Affected area	Symptoms
   Mouth, throat	Stomatitis, sore throat
   Digestive organs	Nausea, vomiting, stomach discomfort, heartburn, loss of appetite, diarrhea
   Skin	Rashes, redness, itching
   Neuropsychiatric system	Headache, dizziness, slowed thinking, sleepiness
   Circulatory organs	Palpitations
   Others	Chest discomfort, irritation of the chest, face redness, face edema, feeling ill

3. Stop using toheart2 パチスロ and consult a physician, dentist, pharmacist, or registered salesperson if the following symptoms appear after using toheart2 パチスロ and continue or worsen. Take this leaflet with you.
   1. Irritation of the mouth and throat, roughness of the tongue, abnormal taste sensation, increased saliva, gingivitis. (These symptoms may become mild if you chew the medicine slowly.)
   2. Pain in the jaw
      (There may be other causes.)
   3. Hiccups, belching
4. The following symptoms may appear if you accidentally use a higher dose than the designated dose of toheart2 パチスロ, or if children accidentally swallow toheart2 パチスロ. In such a case, consult a physician, pharmacist, or registered salesperson. Take this leaflet with you.
   Nausea, increased saliva, abdominal pain, diarrhea, sweating, headache, dizziness, hearing disorder, generalized weakness (possibility of acute nicotine poisoning)
5. If you continue to use toheart2 パチスロ for more than 3 months, consult a physician, pharmacist, or registered salesperson. Take this leaflet with you.
   (Nicotine dependence may occur with prolonged and heavy use of toheart2 パチスロ.)

*Registered salesperson: person who has the license to sell OTC medicines except Category 1.

1. Store in a dry, cool place away from direct sunlight. (If stored in a hot place, the gum sticks to the sheet and toheart2 パチスロ becomes difficult to take toheart2 パチスロ out.)
2. This medicine has a package to prevent children from opening toheart2 パチスロ easily, but keep out of the reach of children.
3. To prevent improper use or loss of quality, do not transfer the medicine to another container.
4. Do not use toheart2 パチスロ after the expiration date.
5. After chewing, throw away the gum after wrapping toheart2 パチスロ in paper, etc., in a place out of the reach of children.